Inventors:
Shaker A. Mousa - Wynantskill NY, US
Paul J. Davis - West Sand Lake NY, US
Aleck Hercbergs - Beachwood OH, US
International Classification:
A61K 9/14, A61K 31/704, A61K 31/7048, A61K 31/66, A61K 31/505, A61K 33/24, A61K 31/337, A61K 31/7072, A61K 31/282, A61K 31/4353, A61K 31/69, A61P 35/00
US Classification:
424489, 514 34, 514 27, 514110, 514274, 424649, 514449, 514 49, 514492, 514283, 514 64
Abstract:
Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.