DR. ALDO N SERAFINI, MD
Radiology at 12 Ave, Miami, FL
License number
Florida ME20026
Category
Radiology
Type
Nuclear Radiology
Address
Address
1611 NW 12Th Ave, Miami, FL 33136
Phone
(305) 243-6358
(305) 243-8470 (Fax)
(305) 243-8470 (Fax)
Professional information
Professor At University Of Miami
Position:
Professor at University of Miami
Location:
Miami/Fort Lauderdale Area
Industry:
Medical Practice
Work:
University of Miami
-
Professor
Professor At University Of Miami
Position:
professor at University of Miami
Location:
Miami/Fort Lauderdale Area
Industry:
Hospital & Health Care
Work:
University of Miami
-
professor
Aldo Nicola Serafini, Miami FL
Specialties:
Internal Medicine, Nuclear Medicine, Nuclear Cardiology, Radiology, Diagnostic Radiology, Nuclear Radiology
Work:
Sylvester Comprehensive Cancer Center
1475 NW 12Th Ave, Miami, FL 33136 Jackson Memorial Hospital
1611 NW 12Th Ave, Miami, FL 33136
1475 NW 12Th Ave, Miami, FL 33136 Jackson Memorial Hospital
1611 NW 12Th Ave, Miami, FL 33136
Education:
University Of The Witwatersrand (1966) Nuclear Medicine
Dr. Aldo N Serafini - MD (Doctor of Medicine)
Hospitals:
University Miami Hospital Rdlgy
1611 NW 12Th Ave STE W279, Miami 33136
University Miami Hospital Rdlgy
1611 NW 12Th Ave STE W279, Miami 33136
1611 NW 12Th Ave STE W279, Miami 33136
University Miami Hospital Rdlgy
1611 NW 12Th Ave STE W279, Miami 33136
Education:
Medical Schools
University of The Witwatersrand/Faculty of Health Sciences
University of The Witwatersrand/Faculty of Health Sciences
Methods Of Achieving Transplantation Tolerance Through Radioablation Of Hemolymphopoietic Cell Populations
US Patent:
2003022, Dec 11, 2003
Filed:
Dec 10, 2002
Appl. No.:
10/316790
Inventors:
Luca Inverardi - Miami Beach FL, US
Camillo Ricordi - Miami FL, US
Giovanni Paganelli - Milano, IT
Aldo Serafini - Key Biscayne FL, US
Jaime Simon - Angleton TX, US
Alan Strickland - Lake Jackson TX, US
Camillo Ricordi - Miami FL, US
Giovanni Paganelli - Milano, IT
Aldo Serafini - Key Biscayne FL, US
Jaime Simon - Angleton TX, US
Alan Strickland - Lake Jackson TX, US
International Classification:
A61K051/00
US Classification:
424/001490
Abstract:
A method for achieving hemolymphopoietic chimerism is disclosed. The method involves the steps of administering to a recipient a bone seeking radiopharmaceutical; transplanting bone marrow-derived cells into the recipient; and transiently suppressing lymphocyte response so as to induce hemolymphopoietic chimerism. The method is useful for decreasing rejection of transplanted organs, tissues or cells and for treating autoimmune diseases. The present invention has the advantage of inducing hemolymphopoietic chimerism without the need for external radiation or harsh cytotoxic drugs. The present invention has the additional advantage of significantly prolonging tolerance to an organ, cell, or tissue transplant.
Methods Of Achieving Transplantation Tolerance Through Radioablation Of Hemolymphopoietic Cell Populations
US Patent:
2003000, Jan 2, 2003
Filed:
Jun 11, 2002
Appl. No.:
10/166053
Inventors:
Luca Inverardi - Miami Beach FL, US
Camillo Ricordi - Miami FL, US
Giovanni Paganelli - Milano, IT
Aldo Serafini - Key Biscayne FL, US
Camillo Ricordi - Miami FL, US
Giovanni Paganelli - Milano, IT
Aldo Serafini - Key Biscayne FL, US
International Classification:
A61K049/00
US Classification:
424/009100
Abstract:
Non-lethal methods of conditioning a recipient prior to bone marrow transplantation to achieve highly enhanced, stable, long-term hematopoietic chimerism in presence of transient immunosuppression are described. In particular, the administration of non-lethal doses of bone-seeking radiopharmaceuticals such as Samarium Lexidronam, a radioactive compound linked to a tetraphosphonate group, to target bone marrow cells, are disclosed herein.