DR. ALBERT F. LOBUGLIO, M.D.
Osteopathic Medicine at 6 Ave, Birmingham, AL

License number
Alabama 10824
Category
Osteopathic Medicine
Type
Hematology & Oncology
Address
Address
6Th Ave S NP 2556, Birmingham, AL 35233
Phone
(205) 934-5077
(205) 975-7428 (Fax)
(205) 394-5077
National Provider ID: 1003175399
LicenseFiles verified this license of Nov 7, 2017 at the National Plan and Provider Enumeration System.

Personal information

See more information about ALBERT F. LOBUGLIO at radaris.com
Name
Address
Phone
Albert F Lobuglio, age 59
2204 Tanglewood Rd, Vestavia, AL 35216
(205) 979-1247
Albert Lobuglio
2204 Tanglewood, Shelby, AL 35143
(205) 979-1247

Organization information

See more information about ALBERT F. LOBUGLIO at bizstanding.com

Albert F Lobuglio

2204 Tanglewood Rd, Birmingham, AL 35216

Status:
Inactive
Industry:
Nonclassifiable Establishments
Doing business as:
Albert F Lobuglio MD
Phone:
(205) 979-1247 (Phone)
Categories:
Internal Medicine Physicians & Surgeons, Oncology Physicians & Surgeons

Professional information

Albert Lobuglio Photo 1

Melanoma Antigens And Methods Of Use

US Patent:
6677444, Jan 13, 2004
Filed:
Oct 18, 2000
Appl. No.:
09/691538
Inventors:
Theresa Strong - Birmingham AL
Robert M. Conry - Birmingham AL
Albert F. LoBuglio - Birmingham AL
Assignee:
UAB Research Foundation - Birmingham AL
International Classification:
C07H 2104
US Classification:
536 235, 435325, 4353201, 536 2431
Abstract:
The present invention provides for isolated DNA and protein corresponding to novel melanoma tumor-associated antigens, antibodies directed towards the novel antigens of the present invention as well as methods of using the antigens for inhibiting the growth of a melanoma tumor and methods of screening compounds that inhibit the novel antigens of the present invention.

Albert F Lobuglio Photo 2

Dr. Albert F Lobuglio, Birmingham AL - MD (Doctor of Medicine)
Specialties:
Hematology, Medical Oncology, Oncology
Address:
1824 6Th St S SUITE 237, Birmingham 35205
(205) 934-5077 (Phone), (205) 975-7428 (Fax)
UNIVERSITY OF ALA AT BIRMINGHAM
1824 6Th Ave S SUITE 237, Birmingham 35205
(205) 934-5077 (Phone), (205) 975-7428 (Fax)
Certifications:
Hematology, 1974, Internal Medicine, 1970, Medical Oncology, 1973
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Georgetown University
Graduated: 1962
Upmc-Presbyterian
Thorndike Meml Lab-Boston C

Albert Lobuglio Photo 3

Melanoma Antigens And Methods Of Use

US Patent:
2004013, Jul 15, 2004
Filed:
Jan 9, 2004
Appl. No.:
10/754820
Inventors:
Theresa Strong - Birmingham AL, US
Robert Conry - Birmingham AL, US
Albert LoBuglio - Birmingham AL, US
Assignee:
UAB Research Foundation
International Classification:
A61K039/395
US Classification:
424/155100
Abstract:
The present invention provides for isolated DNA and protein corresponding to novel melanoma tumor-associated antigens, antibodies directed towards the novel antigens of the present invention as well as methods of using the antigens for inhibiting the growth of a melanoma tumor and methods of screening compounds that inhibit the novel antigens of the present invention.

Albert Francis Lobuglio Photo 4

Albert Francis Lobuglio, Birmingham AL
Specialties:
Internal Medicine, Hematology, Medical Oncology
Work:
U Ala. Birmingham-Anes
 1802 6Th Ave S, Birmingham, AL 35249
Education:
Georgetown University (1962)

Albert Lobuglio Photo 5

Combinations Of Antibodies Selective For Dr5 And Other Therapeutic Agents

US Patent:
7704502, Apr 27, 2010
Filed:
May 22, 2007
Appl. No.:
11/752153
Inventors:
Tong Zhou - Birmingham AL, US
Kimihisa Ichikawa - Kanagawa-ken, JP
Robert P. Kimberly - Birmingham AL, US
William J. Koopman - Indian Springs AL, US
Jun Ohsumi - Kanagawa-ken, JP
Albert F. LoBuglio - Birmingham AL, US
Donald J. Buchsbaum - Alabaster AL, US
Assignee:
The UAB Research Foundation - Birmingham AL
International Classification:
A61K 39/395, C07K 16/28, C07K 16/30
US Classification:
4241431, 4241381, 5303871, 53038822, 5303888, 530350, 53038885
Abstract:
An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Methods and uses for the antibodies, optionally in combination with various therapeutic agents, are detailed, including treatment of apoptosis-related disease and treatment of dysregulated cell growth.

Albert Lobuglio Photo 6

Antibody Selective For Dr4 And Uses Thereof

US Patent:
7476383, Jan 13, 2009
Filed:
Oct 31, 2002
Appl. No.:
10/286132
Inventors:
Tong Zhou - Birmingham AL, US
Robert P. Kimberly - Birmingham AL, US
William J. Koopman - Indian Springs AL, US
Albert F. Lobuglio - Birmingham AL, US
Donald J. Buchsbaum - Montevallo AL, US
Assignee:
The UAB Research Foundation - Birmingham AL
International Classification:
C07K 16/28, C07K 16/30, A61K 39/395
US Classification:
4241431, 4241381, 5303871, 53038822, 5303888, 530350, 5303873, 435334, 435344
Abstract:
An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of DR5 and DR4 antibodies have been elucidated and vectors and cells containing and expressing these sequences have been generated. Methods and uses for the antibodies are detailed including treatment of apoptosis-related disease and treatment of dysregulated cell growth.

Albert Lobuglio Photo 7

Combinations Of Dr5 Antibodies And Other Therapeutic Agents

US Patent:
7279160, Oct 9, 2007
Filed:
Oct 25, 2002
Appl. No.:
10/281479
Inventors:
Tong Zhou - Birmingham AL, US
Kimihisa Ichikawa - Kanagawa-Ken, JP
Robert P. Kimberly - Birmingham AL, US
William J. Koopman - Indian Springs AL, US
Jun Ohsumi - Kanagawa-ken, JP
Albert F. Lobuglio - Birmingham AL, US
Donald J. Buchsbaum - Alabaster AL, US
Assignee:
The UAB Research Foundation - Birmingham AL
International Classification:
C07K 16/28, C07K 16/30, A61K 39/395
US Classification:
4241431, 4241381, 5303871, 53038822, 5303888, 530350, 53038885
Abstract:
An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Methods and uses for the antibodies, optionally in combination with various therapeutic agents, are detailed, including treatment of apoptosis-related disease and treatment of dysregulated cell growth.

Albert Lobuglio Photo 8

Targeting Cancer Stem Cells

US Patent:
2013000, Jan 3, 2013
Filed:
Mar 18, 2011
Appl. No.:
13/634401
Inventors:
Donald J. Buchsbaum - Alabaster AL, US
Albert F. Lobuglio - Birmingham AL, US
Tong Zhou - Birmingham AL, US
Kimberly Foreman - Clarendon Hills IL, US
Assignee:
LOYOLA UNIVERSITY CHICAGO - Maywood IL
THE UAB RESEARCH FOUNDATION - Birmingham AL
International Classification:
A61K 39/395, G01N 33/573, A61N 5/10, A61P 35/00, A61P 35/04, G01N 33/574, A61K 31/7105
US Classification:
4241741, 435 723, 435 74, 514 44 A, 600 1
Abstract:
Provided is a method of determining the level of resistance or sensitivity of cancer stem cells to a death receptor agonist. The method includes detecting the level of IAP in one or more DR5/DDX3/IAP complexes in or from the cancer stem cells. Also provided is a method of killing cancer stem cells in a subject and a method of reducing the risk of cancer recurrence in a subject.

Albert Lobuglio Photo 9

Treating Basal-Like Genotype Cancers

US Patent:
2011010, May 5, 2011
Filed:
Nov 5, 2010
Appl. No.:
12/940746
Inventors:
Donald J. Buchsbaum - Alabaster AL, US
Tong Zhou - Birmingham AL, US
Albert F. LoBuglio - Birmingham AL, US
Assignee:
THE UAB RESEARCH FOUNDATION - Birmingham AL
International Classification:
A61K 39/395, C07K 16/18, A61P 35/00, G01N 33/574
US Classification:
4241301, 5303891, 435 723
Abstract:
Provided herein are methods of treating a subject with cancer comprising administering to the subject a death receptor agonist. Also provided herein are methods of screening a breast cancer cell for responsiveness to a DR5 agonist. Further provided herein are antibodies that selectively bind an N-terminal CARD of DDX3, a DDX3 lacking an N-terminal CARD, and an 80 kDa baculovirus TAP repeat (BIR).

Albert Lobuglio Photo 10

Antibody Selective For Dr4 And Uses Thereof

US Patent:
2009020, Aug 20, 2009
Filed:
Aug 7, 2008
Appl. No.:
12/187818
Inventors:
Tong Zhou - Birmingham AL, US
Robert P. Kimberly - Birmingham AL, US
William J. Koopman - Indian Springs AL, US
Albert F. LoBuglio - Birmingham AL, US
Donald J. Buchsbaum - Alabaster AL, US
Assignee:
THE UAB RESEARCH FOUNDATION - Birmingham AL
International Classification:
A61K 39/395, C07K 16/00, C07K 16/28, C12N 5/02, C12N 13/00
US Classification:
4241301, 5303871, 53038822, 5303877, 5303873, 435375, 4351731
Abstract:
An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of DR5 and DR4 antibodies have been elucidated and vectors and cells containing and expressing these sequences have been generated. Methods and uses for the antibodies are detailed including treatment of apoptosis-related disease and treatment of dysregulated cell growth.

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