ALBEE MESSING
Veterinary in Madison, WI
License number
Pennsylvania BV004628L
Category
Veterinary Medicine
Type
Veterinarian
Address
Address
2
Madison, WI 53706
Pennsylvania
Pennsylvania
Professional information
Professor At University Of Wisconsin Madison
Position:
Professor at University of Wisconsin Madison
Location:
Madison, Wisconsin Area
Industry:
Information Technology and Services
Work:
University of Wisconsin Madison
-
Professor
Mx-1 Conditionally Immortalized Cells
US Patent:
6392118, May 21, 2002
Filed:
May 23, 1995
Appl. No.:
08/447997
Inventors:
Joseph P. Hammang - Barrington RI
Albee Messing - Madison WI
Albee Messing - Madison WI
Assignee:
Neurotech S.A. - Evry
International Classification:
A01K 67027
US Classification:
800 14, 4353201, 435455, 435325, 424 9321, 800 25
Abstract:
This invention relates to methods and compositions of controlling cell distribution within a bioartificial organ by exposing the cells to a treatment that inhibits cell proliferation, promotes cell differentiation, or affects cell attachment to a growth surface within the bioartificial organ. Such treatments include (1) genetically manipulating cells, (2) exposing the cells to a proliferation-inhibiting compound or a differentiation-inducing compound or removing the cells from exposure to a proliferation-stimulating compound or a differentiation-inhibiting compound; exposing the cells to irradiation, and (3) modifying a growth surface of the BAO with ECM molecules, molecules affecting cell proliferation or adhesion, or an inert scaffold, or a combination thereof. These treatments may be used in combination.
Transgentic Mouse Expressing Green Fluorescent Protein In Glial Cells
US Patent:
6501003, Dec 31, 2002
Filed:
Jul 8, 1998
Appl. No.:
09/111667
Inventors:
Albee Messing - Madison WI
Lang Zhuo - Middleton WI
Lang Zhuo - Middleton WI
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 6700
US Classification:
800 18, 800 3
Abstract:
A transgenic mammal, specifically a mouse, containing in its genome a humanized mutant of green fluorescent protein operably linked to the glial fibrillary acidic protein promoter is provided. The mouse can be used to assay the effects of systemic or topical administration of neurotoxins and also to assay the effects of physical damage to neural tissue.
Mx-1 Conditionally Immortalized Cells
US Patent:
6495364, Dec 17, 2002
Filed:
Mar 7, 2001
Appl. No.:
09/801237
Inventors:
Joseph P. Hammang - Barrington RI
Albee Messing - Madison WI
Albee Messing - Madison WI
Assignee:
Neurotech, S.A. - Evry
International Classification:
C12N 1500
US Classification:
4353201, 435325, 435455, 514 44, 424 932
Abstract:
This invention relates to methods and compositions of controlling cell distribution within a bioartificial organ by exposing the cells to a treatment that inhibits cell proliferation, promotes cell differentiation, or affects cell attachment to a growth surface within the bioartificial organ. Such treatments include (1) genetically manipulating cells, (2) exposing the cells to a proliferation-inhibiting compound or a differentiation-inducing compound or removing the cells from exposure to a proliferation-stimulating compound or a differentiation-inhibiting compound; exposing the cells to irradiation, and (3) modifying a growth surface of the BAO with ECM molecules, molecules affecting cell proliferation or adhesion, or an inert scaffold, or a combination thereof. These treatments may be used in combination.
Suppression Of Glial Fibrillary Acidic Protein
US Patent:
2013022, Aug 29, 2013
Filed:
Feb 4, 2013
Appl. No.:
13/758796
Inventors:
Albee Messing - Madison WI, US
Woosung Cho - Plano TX, US
Jon Scott Thorson - Lexington KY, US
Randal D. Goff - Pace FL, US
Woosung Cho - Plano TX, US
Jon Scott Thorson - Lexington KY, US
Randal D. Goff - Pace FL, US
International Classification:
A61K 31/56, A61K 31/352, A61K 31/135, A61K 31/55
US Classification:
514169, 435375, 514217, 514456, 514649
Abstract:
Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell. Also provided are compounds useful for the treatment of Alexander disease in subjects at risk of or diagnosed with Alexander disease and methods for the identification of such compounds.
Suppression Of Glial Fibrillary Acidic Protein
US Patent:
8372808, Feb 12, 2013
Filed:
Oct 26, 2009
Appl. No.:
12/589638
Inventors:
Albee Messing - Madison WI, US
Woosung Cho - Madison WI, US
Jon Scott Thorson - Middleton WI, US
Randal D. Goff - Madison WI, US
Woosung Cho - Madison WI, US
Jon Scott Thorson - Middleton WI, US
Randal D. Goff - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
A61K 38/00, A61K 31/715, A61K 31/675, A61K 31/66, A61K 31/59
US Classification:
514 121, 514 61, 514 80, 514118, 514167, 514182, 514183, 514217, 514 225, 514256, 5142592
Abstract:
Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell. Also provided are compounds useful for the treatment of Alexander disease in subjects at risk of or diagnosed with Alexander disease and methods for the identification of such compounds.