Inventors:
Francisco Villarreal - Chula Vista CA, US
Alan Maisel - Solana Beach CA, US
George Schreiner - Los Altos Hills CA, US
Guillermo M. Ceballos Reyes - Medico D.F., MX
Pam Taub - Rancho Santa Fe CA, US
International Classification:
A61K 31/455, A61K 31/573, A61K 45/06, A61K 31/353
US Classification:
424649, 514456, 514355, 514220, 51425941, 51421113, 514 50, 514330, 514369, 514 34, 514350, 514158, 514420, 5142265, 514342, 514354, 514274, 514 49, 51425405, 5142634, 514 45, 51425407, 514 81, 514 40, 514 205, 514110, 514171
Abstract:
The present invention relates to compositions and methods for prophylactic and/or therapeutic treatment of conditions related to mitochondrial function. In various aspects, the present invention comprises administering one or more compounds selected from the group consisting of epicatechin, an epicatechin derivative, catechin, a catechin derivative, nicorandil, and a nicorandil derivative in an amount effective to ameliorate mitochondrial toxicity caused by administration of a chemical, food, or drug.