ALAN K COHEN
Chiropractic in Newton, MA

6650932, Nov 18, 2003

May 15, 2000

09/570683

Wayne Y. Menzie - Arlington MA
John Schafer - North Hampton NH
Alan M. Cohen - Newton MA

Boston Medical Technologies, Inc. - Wakefield MA

A61B 50205

600513, 607 25

A medical testing system includes telemetry features whereby physiological data collected by a collection device at a medical facility is transmitted to a remote processing center for analysis by a trained analyst to provide a test result. In one embodiment, the collection device is a heart rate monitor capable of collecting data with which heart rate variability can be assessed. The heart rate monitor includes a display on which is displayed a waveform showing the breathing performance of the patient during data collection along with standards against which to compare the waveform in order to determine the extent to which the patient followed a predetermined breathing regimen during data collection. The operator of the monitor can use the performance waveform to assess how well the test was taken (i. e. , how well the patient complied with the prescribed breathing regimen) and can accept or reject the physiological data accordingly.

6436053, Aug 20, 2002

Feb 18, 2000

09/507770

Alan M. Cohen - Newton MA

Boston Medical Technologies, Inc. - Wakefield MA

A61B 508

600538, 600529

A system for enhancing patient compliance with a predetermined breathing pattern during inspiration measurements utilizes patient feedback based on inspiration flow. The measured inspiration flow is displayed on a first display and a target inspiration flow is display on a second display, preferably, disposed adjacent to the first display to facilitate visual comparison. The patient is instructed to breathe in manner that causes the measured inspiration flow display to match, or flow the target inspiration flow display.

6740046, May 25, 2004

Jul 16, 2002

10/195956

Alan M. Cohen - Newton MA

Boston Medical Technologies, Inc. - Wakefield MA

A61B 508

600538, 600529

A system for enhancing patient compliance with a predetermined breathing pattern during inspiration measurements utilizes patient feedback based on inspiration flow. The measured inspiration flow is displayed on a first display and a target inspiration flow is displayed on a second display, preferably, disposed adjacent to the first display to facilitate visual comparison. The patient is instructed to breathe in a manner that causes the measured inspiration flow display to match, or follow the target inspiration flow display.

6416473, Jul 9, 2002

Jun 13, 2000

09/592955

Marcelo R. Risk - Melrose MA
Alan M. Cohen - Newton MA
Daniel T. Kaplan - St. Paul MN

Boston Medical Technologies, Inc. - Wakefield MA

A61B 500

600300, 600485, 600301, 600500, 600509, 600521

Methods and apparatus for providing a single, accurate indicator of a patients autonomic nervous system function are described. The indicator is a combination of results of a plurality of different autonomic nervous system tests performed on the patient and referenced to a cross-sectional population. In one embodiment, the results of the different autonomic nervous system tests are referenced to a limited age group of the cross-sectional population. A method according to the invention includes generating a mathematical expression for each of the autonomic nervous system tests as a function of physiological data of the cross-sectional population, inserting measured physiological data of the patient into the mathematical expressions to compute output values for each of the tests, and combining the output values to provide the autonomic function indicator.

2004010, Jun 3, 2004

Jun 30, 2003

10/610495

Wayne Menzie - Medford MA, US
John Schafer - North Hampton NH, US
Keith Knapp - Townsend MA, US
Alan Cohen - Newton MA, US

A61B005/0402

600/509000

A medical testing system includes telemetry features whereby physiological data collected by a collection device at a medical facility is transmitted to a remote processing center for analysis by a trained analyst to provide a test result. In one embodiment, the collection device is a heart rate monitor capable of collecting data with which heart rate variability can be assessed. The heart rate monitor includes a display on which is displayed a waveform showing the breathing performance of the patient during data collection along with standards against which to compare the waveform in order to determine the extent to which the patient followed a predetermined breathing regimen during data collection. The operator of the monitor can use the performance waveform to assess how well the test was taken (i.e., how well the patient complied with the prescribed breathing regimen) and can accept or reject the physiological data accordingly. Also described is a medical testing telemetry system including two processing centers, with each collection device being capable of communicating with both processing centers. Each collection device randomly chooses one of the processing centers for analysis of the collected physiological data. The two processing centers are interconnected in order to permit physiological data and test results to be replicated and stored at both sites.

4816388, Mar 28, 1989

Oct 30, 1985

6/792817

Jean D. Sipe - Roslindale MA
Alexander S. Whitehead - Needham MA
Alan S. Cohen - Newton MA
Martha Skinner - Chestnut Hill MA

Children's Medical Center Corporation - Boston MA

C12Q 168, C07H 1512, C12N 1500

435 6

Recombinant human prealbumin and a method for producing such human prealbumin through recombinant DNA techniques including preparation and isolation of a cDNA sequence coding for human prealbumin, construction of a cloning vector and an expression vector containing said cDNA sequence, and expression of human prealbumin in a prokaryotic cell transformed by said expression vector are disclosed. The invention further relates to the use of human prealbumin cDNA in the diagnosis by hybridization methodologies of medical conditions with which variant forms of prealbumin are associated. Also disclosed is a method for diagnosing some Type I familial amyloid polyneuropathies by a restriction endonuclease assay with an enzyme which recognizes the nucleotide base sequence 5'-ATGCAT-3'.

2002001, Feb 14, 2002

Jun 25, 2001

09/891572

Alan Cohen - Newton MA, US
Marcelo Risk - Melrose MA, US
Wayne Menzie - Medford MA, US
Keith Knapp - Townsend MA, US
John Schafer - Hampton NH, US

G01N033/00

702/030000, 436/095000, 422/068100, 422/067000

A glucose meter includes means for processing a blood sample to provide a glucose measurement and a communication interface to send and receive data including the glucose measurement to a remote processing center. The processing center collects and processes a plurality of glucose measurements to provide a modified method for processing a blood sample in order to provide an adjusted glucose measurement. In one embodiment, the modified blood sample processing method is a function of a permissible glucose deviation for the patient and in another embodiment, the modified blood sample processing method is a function an aging factor indicative of test strip variations over time.

7522574, Apr 21, 2009

May 4, 2007

11/800135

Andrea R. Biagioni - Melrose MA, US
Alan M. Cohen - Newton MA, US
Jeffrey R. Thumm - Norfolk MA, US

Omni Medics Corporation - Melrose MA

H04Q 7/00

370338, 370310, 370311, 370318, 370335, 455502, 4555501, 455574, 600300

A monitoring system comprises a specific remote unit or monitor and a plurality of base stations that are capable of communicating with one another. A designated one of the plurality of base stations transmits a message via a wireless medium to the specific remote unit on behalf of the plurality of base stations, and the plurality of base stations use a shared base station identifier or shared sender address for communication with the specific remote unit or monitor. In another aspect, a first designated one transmits a message during a first time period and a second designated one transmits a message during a second time period. Receiving messages from a designated one of the plurality of base stations using the shared base station identifier helps the specific remote unit or monitor to reduce its power usage.