Inventors:
Martin C. Carey - Wellesley MA
Alan C. Moses - Waban MA
Jeffrey S. Flier - Newton MA
Assignee:
Beth Israel Hospital - Boston MA
The Brigham & Women's Hospital, Inc. - Boston MA
International Classification:
A61K 3726, A61K 3156
Abstract:
A composition useful for the treatment of an animal suffering from a predetermined medical disorder including, in admixture, a medically effective amount of a drug, other than an antibiotic, effective against the medical disorder, and a biocompatible, water-soluble, amphiphilic steroid, other than a bile salt, which is capable of increasing the permeability to the drug of a surface of the animal across which the drug is to be administered, in an amount effective to increase the permeability of the surface to the drug.