ALAIN H ROOK
Medical Practice in Penn Wynne, PA
License number
Pennsylvania MD039521E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Penn Wynne, PA 19096
Personal information
See more information about ALAIN H ROOK at radaris.comName
Address
Phone
455 Ballytore Rd, Wynnewood, PA 19096
Wynnewood, PA
3400 Spruce St, Philadelphia, PA 19104
455 Ballytore Rd, Wynnewood, PA 19096
Professional information
Formulations And Methods Of Treatment Of Skin Conditions
US Patent:
2013021, Aug 15, 2013
Filed:
Apr 20, 2011
Appl. No.:
13/695902
Inventors:
Alfonso J. Tobia - Doylestown PA, US
Bernard E. Cabana - Biglerville PA, US
Alain H. Rook - Wynnewood PA, US
Bernard E. Cabana - Biglerville PA, US
Alain H. Rook - Wynnewood PA, US
Assignee:
Hy Biopharma, Inc. - Jamison PA
International Classification:
A61N 5/06
US Classification:
604501, 514680, 514455
Abstract:
A liquid or ointment formulation for the treatment of a skin condition associated with leukocyte accumulation in the skin includes a therapeutic compound selected to reduce leukocyte accumulation in the skin and an aqueous solution of an organic solvent. The organic solvent increases skin permeability. A method of treating a skin condition associated with leukocyte accumulation in the skin includes the steps of applying topically a liquid formulation of a photosensitizer to a skin lesion of a patient afflicted with the skin condition and exposing the skin lesion to a light source.
Methods For Treatment Of Cutaneous T-Cell Lymphoma
US Patent:
7052685, May 30, 2006
Filed:
Oct 15, 1999
Appl. No.:
09/419328
Inventors:
Alain H. Rook - Wynnewood PA, US
Assignee:
Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
A61K 45/00
US Classification:
424 852, 424 854, 424 851
Abstract:
A method and composition for treatment of advanced cutaneous T cell lymphoma is provided which involves administration of recombinant interleukin-12.
Treatment For Cutaneous T Cell Lymphoma
US Patent:
2009024, Oct 1, 2009
Filed:
Dec 28, 2006
Appl. No.:
12/159058
Inventors:
Alain H. Rook - Wynnewood PA, US
Bernice M. Benoit - Prospect Park PA, US
Maria Wysocka - Drexel Hill PA, US
Sarah M. Bray - Pittsburgh PA, US
Richard L. Miller - Maplewood MN, US
Mark A. Tomai - Woodbury MN, US
Bernice M. Benoit - Prospect Park PA, US
Maria Wysocka - Drexel Hill PA, US
Sarah M. Bray - Pittsburgh PA, US
Richard L. Miller - Maplewood MN, US
Mark A. Tomai - Woodbury MN, US
International Classification:
A61K 38/21, C12N 5/06, A61K 31/4745
US Classification:
424 855, 435375, 514293, 424 857
Abstract:
The present invention provides method for treating a patient with cutaneous T cell lymphoma (CTCL). Generally, the methods include administering to the patient an IRM compound in an amount effective to ameliorate at least one symptom or clinical sign of CTCL. In some embodiments, the methods also include administering to the patient a priming dose of a Type I interferon. In another aspect, the invention provides methods of increasing a cell-mediated immune response of a cell population that includes cells affected by cutaneous T cell lymphoma. Generally, the methods include contacting the cell population with an IRM compound in an amount effective to increase at least one cell-mediated immune activity of the cell population. In some embodiments, the methods include contacting the cell population with a priming dose of a Type I interferon.
Photoactivated Hypericin And The Use Thereof
US Patent:
6001882, Dec 14, 1999
Filed:
Jul 3, 1997
Appl. No.:
8/887546
Inventors:
Floyd Eliot Fox - Bellmawr NJ
Alain H. Rook - Wynnewood PA
Alfonso J. Tobia - Doylestown PA
Alain H. Rook - Wynnewood PA
Alfonso J. Tobia - Doylestown PA
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
A61K 3112
US Classification:
514680
Abstract:
The invention provides methods of using photoactivated hypericin compounds which, when photoactivated using visible or UV-A light, are useful for treating numerous diseases and disorders in mammals. The compounds of the invention are useful for inhibiting the proliferation and accumulation of mammalian leukocytes and for inducing apoptosis in mammalian leukocytes.