AJAY VERMA
Medical Practice in Harleysville, PA
License number
Pennsylvania MD056148L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Harleysville, PA 19438
Personal information
See more information about AJAY VERMA at radaris.comName
Address
Phone
2169 Henley Cmn, Southampton, PA 18966
2169 Henley Cmn, Southampton, PA 18966
2169 Henley, Northampton, PA 18966
3300 Neshaminy Blvd, Bensalem, PA 19020
401 Hoffman Rd, Harleysville, PA 19438
Professional information
Activation Of Hypoxia-Inducible Gene Expression
US Patent:
2007017, Jul 26, 2007
Filed:
Nov 8, 2004
Appl. No.:
10/578438
Inventors:
Ajay Verma - Harleysville PA, US
Huasheng Lu - Boyds MD, US
Robert Forbes - Princeton NJ, US
Clifton Dalgard - San Francisco CA, US
Ahmed Mohyeldin - Washington DC, US
Ronald Zenk - Eden Prairie MN, US
Huasheng Lu - Boyds MD, US
Robert Forbes - Princeton NJ, US
Clifton Dalgard - San Francisco CA, US
Ahmed Mohyeldin - Washington DC, US
Ronald Zenk - Eden Prairie MN, US
International Classification:
A61K 31/19, A61K 31/21, C12N 15/01
US Classification:
514506000, 435441000, 514557000
Abstract:
The present invention relates to the elucidation of specific molecular features of endogenous 2-oxoacid molecules and their derivatives for activating hypoxia-inducible gene expression by inactivating hypoxia-inducible factor hydroxylating enzymes. This invention identifies agents that can be used to induce tissue vascularization, treat anemias, induce tolearance to stroke and heart attacks, improve tissue healing and improve organ transplantation.
Methods For Lowering Hif-1 Mediated Gene Expression
US Patent:
2008004, Feb 21, 2008
Filed:
Oct 25, 2005
Appl. No.:
11/666229
Inventors:
Ajay Verma - Harleysville PA, US
Huasheng Lu - Boyds MD, US
Huasheng Lu - Boyds MD, US
International Classification:
A61K 31/195, A61K 31/34, A61K 31/415, A61K 38/00, A61P 43/00
US Classification:
514018000, 514399000, 514474000, 514562000
Abstract:
The present invention relates to the elucidation of specific molecular features of endogenous amino acids and their derivatives for inhibiting hypoxia-inducible gene expression by preventing inactivation of hypoxia-inducible factor hydroxylating enzymes. This invention encompasses agents that can be used to reduce tissue vascularization, cancer cell survival, and to treat obesity.