AILEEN CLEARY COHEN, MD
Medical Practice at Welch Rd, Palo Alto, CA
License number
California A66875
Category
Medical Practice
Type
Pediatric Hematology-Oncology
Address
Address
725 Welch Rd, Palo Alto, CA 94304
Phone
(650) 497-8000
Professional information
Aileen Cleary Cohen, Palo Alto CA
Specialties:
Pediatrician
Address:
725 Welch Rd, Palo Alto, CA 94304
Education:
Doctor of Medicine
Board certifications:
American Board of Pediatrics Certification in Pediatrics
Dr. Aileen C Cohen, Palo Alto CA - MD (Doctor of Medicine)
Specialties:
Pediatrics
Address:
725 Welch Rd, Palo Alto 94304
(650) 497-8953 (Phone), (650) 497-8101 (Fax)
300 Pasteur Dr, Palo Alto 94304
(650) 723-5535 (Phone)
(650) 497-8953 (Phone), (650) 497-8101 (Fax)
300 Pasteur Dr, Palo Alto 94304
(650) 723-5535 (Phone)
Certifications:
Pediatrics, 2006
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Columbia University / College of Physicians And Surgeons
Columbia University / College of Physicians And Surgeons
Methods For Diagnosis, Prognosis And Methods Of Treatment
US Patent:
2012030, Dec 6, 2012
Filed:
Jun 11, 2012
Appl. No.:
13/493857
Inventors:
Wendy J. Fantl - San Francisco CA, US
Santosh K. Putta - Foster City CA, US
Omar D. Perez - San Francisco CA, US
Helen L. Francis-Lang - San Francisco CA, US
Aileen C. Cohen - Palo Alto CA, US
Santosh K. Putta - Foster City CA, US
Omar D. Perez - San Francisco CA, US
Helen L. Francis-Lang - San Francisco CA, US
Aileen C. Cohen - Palo Alto CA, US
Assignee:
Nodality, Inc. - South San Francisco CA
International Classification:
G01N 33/574, G01N 33/577
US Classification:
435 723
Abstract:
This invention is directed to methods and compositions for diagnosis, prognosis and for determining methods of treatment. The physiological status of cells present in a sample (e.g. clinical sample) can be used in diagnosis or prognosis of a condition (e.g. Chronic Lymphocytic Leukemia), in patient selection for therapy, to monitor treatment and to modify or optimize therapeutic regimens. The physiological status of a cell can be determined by comparing the intracellular status of one or more activation elements (e.g. the phosphorylation status of a signaling molecule) in a cell (e.g. a cancer cell) to that of another cell (e.g. a normal cell). The physiological status of a cell can be further classified by adding one or more modulators (e.g. an inhibitor or activator) to the cell in question. In some embodiments, the invention is directed to methods of determining a phenotypic profile of a population of cells.
Methods For Diagnosis Prognosis And Methods Of Treatment
US Patent:
2009009, Apr 16, 2009
Filed:
Aug 21, 2008
Appl. No.:
12/229476
Inventors:
Wendy J. Fantl - San Francisco CA, US
Santosh K. Putta - Foster City CA, US
Omar D. Perez - San Francisco CA, US
Helen L. Francis-Lang - San Francisco CA, US
Aileen C. Cohen - Palo Alto CA, US
Santosh K. Putta - Foster City CA, US
Omar D. Perez - San Francisco CA, US
Helen L. Francis-Lang - San Francisco CA, US
Aileen C. Cohen - Palo Alto CA, US
Assignee:
Nodality, Inc. - South San Francisco CA
International Classification:
C12Q 1/02
US Classification:
435 29
Abstract:
This invention is directed to methods and compositions for diagnosis, prognosis and for determining methods of treatment. The physiological status of cells present in a sample (e.g. clinical sample) can be used in diagnosis or prognosis of a condition (e.g. Chronic Lymphocytic Leukemia), in patient selection for therapy, to monitor treatment and to modify or optimize therapeutic regimens. The physiological status of a cell can be determined by comparing the intracellular status of one or more activation elements (e.g. the phosphorylation status of a signaling molecule) in a cell (e.g. a cancer cell) to that of another cell (e.g. a normal cell). The physiological status of a cell can be further classified by adding one or more modulators (e.g. an inhibitor or activator) to the cell in question. In some embodiments, the invention is directed to methods of determining a phenotypic profile of a population of cells.
Methods For Diagnosis, Prognosis And Methods Of Treatment
US Patent:
2013013, May 23, 2013
Filed:
May 17, 2012
Appl. No.:
13/473829
Inventors:
Wendy J. Fantl - San Francisco CA, US
David B. Rosen - San Francisco CA, US
Alessandra Cesano - Redwood City CA, US
Santosh K. Putta - Foster City CA, US
Garry Nolan - San Francisco CA, US
Aileen Cohen - Palo Alto CA, US
Erik Evensen - Foster City CA, US
David B. Rosen - San Francisco CA, US
Alessandra Cesano - Redwood City CA, US
Santosh K. Putta - Foster City CA, US
Garry Nolan - San Francisco CA, US
Aileen Cohen - Palo Alto CA, US
Erik Evensen - Foster City CA, US
Assignee:
Nodality, Inc. - South San Francisco CA
International Classification:
G01N 33/68
US Classification:
435 723
Abstract:
The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN.
Methods For Diagnosis, Prognosis And Methods Of Treatment
US Patent:
2010000, Jan 14, 2010
Filed:
Jul 10, 2009
Appl. No.:
12/460029
Inventors:
Wendy J. Fantl - San Francisco CA, US
David B. Rosen - San Francisco CA, US
Alessandra Cesano - Redwood City CA, US
Santosh K. Putta - Foster City CA, US
Garry Nolan - San Francisco CA, US
Aileen Cohen - Palo Alto CA, US
Erik Evensen - Foster City CA, US
David B. Rosen - San Francisco CA, US
Alessandra Cesano - Redwood City CA, US
Santosh K. Putta - Foster City CA, US
Garry Nolan - San Francisco CA, US
Aileen Cohen - Palo Alto CA, US
Erik Evensen - Foster City CA, US
Assignee:
Nodality, Inc. - South San Francisco CA
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN.
Method For Determining The Status Of An Individual
US Patent:
2009029, Nov 26, 2009
Filed:
May 22, 2009
Appl. No.:
12/471158
Inventors:
Aileen Cohen - Palo Alto CA, US
Helen Francis-Lang - Sticklepath Nr Okehampton, GB
Malcolm Francis-Lang - Sticklepath Nr Okehampton, GB
Helen Francis-Lang - Sticklepath Nr Okehampton, GB
Malcolm Francis-Lang - Sticklepath Nr Okehampton, GB
Assignee:
Nodality, Inc. - San Francisco CA
International Classification:
G01N 33/53
US Classification:
435 721
Abstract:
Methods of determining status of an individual based on the use of biological specimen and analysis of reference population of cells are described.