Inventors:
Stephen Sturley - New York NY, US
Aaron Turkish - New York NY, US
Jeffrey Billheimer - West Chester PA, US
Debra Cromley - Pittsgrove NJ, US
International Classification:
A61K 38/26, A61K 31/685, A61K 31/553, A61K 31/366, A61K 31/19
US Classification:
514012000, 514078000, 514457000, 514460000, 514557000, 514571000, 514356000, 514211130
Abstract:
This invention provides methods for treating a subject afflicted with acne or another sebaceous gland disorder comprising administering to the subject a therapeutically effective amount of an agent which inhibits acyl-CoA wax alcohol acyltransferase 1 (AWAT1) and/or acyl-CoA wax alcohol acyltransferase 2 (AWAT2), thereby treating the subject. This invention further provides related articles of manufacture and methods.